Accelerating Alzheimer's Disease Breakthroughs With HPC
Dell EMC News, November 28th, 2019
November 28, 2019,
Volume 260, Issue 4

University of Queensland highlights potential of ultrasound to delay the onset of Alzheimer's disease

"The University of Queensland is modeling possible treatments for some of the most debilitating illnesses such as Alzheimer's disease. The Queensland Brain Institute, the University's neuroscience research institute, is using its high performance computing system to model the behavior of ultrasound using an analysis technique called Finite Element Method (FEM).

The modeling calculates what happens to each element of the brain when an ultrasound is passed through the skull. It is hoped that ultrasound can be used to temporarily allow direct delivery of therapeutic drugs to the brain, something not currently possible due to the presence of a blood-brain barrier. The team also hopes to activate cells that can digest the plaques that are a hallmark of Alzheimer's disease. The promising results will now be confirmed in a sheep study, an animal with similar skull properties as humans, and may be instrumental in developing treatments that stop or reserve degeneration, rather than just relieving symptoms..."

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